Background: A fatal outcome occurs in 2% of patients with Reversible Cerebral Vasoconstriction Syndrome (RCVS).Due to its rarity, guidelines for the management of the most severe forms of RCVS are lacking.Case presentation: Here, we describe the case of a 55 year-old woman who died from complications of RCVS and reviewed patients with fatal outcome
Introduction: Lower urinary tract symptoms (LUTS) are highly prevalent in men and the incidence increases with aging.The pathophysiology of LUTS is multifactorial and is characterized by voiding and storage symptoms.Acharya Sushruta described 12 types of Mutraghata along with its management in the form of single drug or compound formulations.Clinic
Plants are subjected to extreme environmental conditions and must adapt rapidly.The phytohormone abscisic acid (ABA) accumulates during abiotic stress, signaling transcriptional changes that trigger physiological responses.Epigenetic WATERMELON modifications often facilitate transcription, particularly at genes exhibiting temporal, tissue-specific
Ethical regulations and limited paediatric participants are key challenges that contribute to a median delay of 6 years in paediatric mAb approval.To overcome these barriers, modelling and simulation methodologies have been adopted to design optimized paediatric clinical studies and reduce patient burden.The classical modelling approach in paediatr